{"title":"Clipping","description":"\u003cp\u003eEverything for clipping cryo-EM grids into autogrids — clipping tools, stations, racks, bottoming tools, rings, C-clips and inspection tools.\u003c\/p\u003e","products":[{"product_id":"long-straight-serrated-tip-dumont-tweezers","title":"Long, Straight Serrated Tip, Dumont Tweezers","description":"\u003cp\u003eA high-quality, long (~6 inch) tweezer with straight, serrated tips, ideal for handling NanoSoft Clipping Tools and for general manipulation of non-fragile items under LN2, i.e. not grids. Can be insulated with high quality insulation to allow comfortable handling during long cryo-sessions.\u003c\/p\u003e","brand":"Dumont","offers":[{"title":"None \/ N\/A","offer_id":49095467467003,"sku":"28011011","price":54.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ White","offer_id":49095467499771,"sku":"28011036","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Black","offer_id":49095467532539,"sku":"28011037","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Blue","offer_id":49095467565307,"sku":"28011041","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Green","offer_id":49095467598075,"sku":"28011038","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Yellow","offer_id":49095467630843,"sku":"28011039","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Red","offer_id":49095467663611,"sku":"28011040","price":94.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-28011011_84a63dc6-ad4b-4a8d-8701-9bf1f12d9168.jpg?v=1784907218"},{"product_id":"long-45-degree-serrated-tip-dumont-tweezers","title":"Long, 45 Degree, Serrated Tip, Dumont Tweezers","description":"\u003cp\u003eA high-quality, long (~6 inch) tweezer with bent (45 degrees) tips, ideal for handling NanoSoft Clipping Tools and for general manipulation of non-fragile items under LN2, i.e. not grids. Can be insulated with high quality insulation to allow comfortable handling during long cryo-sessions.\u003c\/p\u003e","brand":"Dumont","offers":[{"title":"None \/ N\/A","offer_id":49095467696379,"sku":"28011012","price":54.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ White","offer_id":49095467729147,"sku":"28011042","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Black","offer_id":49095467761915,"sku":"28011043","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Blue","offer_id":49095467794683,"sku":"28011047","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Green","offer_id":49095467827451,"sku":"28011044","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Yellow","offer_id":49095467860219,"sku":"28011045","price":94.0,"currency_code":"USD","in_stock":true},{"title":"Insulated \/ Red","offer_id":49095467892987,"sku":"28011046","price":94.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-28011012_b419768c-482d-4f23-a578-8e79771b65eb.jpg?v=1784907218"},{"product_id":"thermo-fisher-cassette-loading-station-repair","title":"Thermo Fisher Cassette Gripper Repair","description":"\u003cp\u003eThe internal plastic insert from Thermo Fisher's cassette loading station, which contains the metal cassette holder where autogrids are loaded, is very prone to cracking. Rather than purchase a brand new loading station, use NanoSoft's Cassette Loading Station repair service. We'll replace that plastic insert with our brand new insert with improved design and materials, leading to a more durable part that will last longer.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095469957371,"sku":"41031001","price":1400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-41041001-1.jpg?v=1786551679"},{"product_id":"thermo-fisher-clipping-station-repair","title":"Thermo Fisher Clipping Station Repair","description":"\u003cp\u003eThe interior plastic bowl of Thermo Fisher’s Clipping Station is susceptible to cracking after repeated use. The only solution from the OEM is to purchase a brand new clipping station, which is expensive. NanoSoft will repair the Clipping Station, providing a like- new Clipping Station for a small percentage of the cost of new one.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095489061115,"sku":"20011001","price":1250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_8f2a92754c974d429f1c3741c4cd3464_mv2.jpg?v=1785391518"},{"product_id":"100-pack-fib-autogrid-rings-c-clips","title":"100-Pack, FIB Autogrid Rings \u0026 C-Clips","description":"\u003cp\u003eOur patented (pending) FIB Autogrid Ring design offers major technical and usability improvements over Thermo Fisher Scientific's FIB ring. Our NanoSoft FIB Autogrid Ring provides a significant increase in the area of your grid accessible for milling with the ion beam, relative to the TFS FIB ring. Instead of a small cut out notch on the back, flat side of the ring to allow for ion beam access for shallow-angled milling, which blocks access to a large portion of the valuable grid, our FIB Autogrid Ring has an angled face around the entire circumference on the \"backside\", providing this incredible increase in accessible area, allowing you to reclaim valuable sample\/cells on your grid.\u003c\/p\u003e\u003cp\u003eFurthermore, whereas many people have resorted to manually marking the TFS FIB ring with a marker, due to the poor visibility of their markings used to orient the ring, our NanoSoft FIB Autogrid Ring has marks with excellent contrast, making correct orientation by eye incredibly easy. Additionally, our NanoSoft FIB Autogrid Ring has matching marks on the \"top face\", so you can see the orientation of the ring when clipping a grid.\u003c\/p\u003e\u003cp\u003eOur FIB Autogrid Rings are manufactured with the same cutting-edge manufacturing techniques as our \"regular\" Autogrid Rings, resulting in similar top-quality, incredibly reliable and consistent parts. Furthermore, we use the same quality and inspection processes, including that every FIB ring gets checked individually by eye by our experts before being shipped to customers.\u003c\/p\u003e\u003cp\u003eThe 3 major differences you'll notice about our rings:\u003c\/p\u003e\u003col\u003e\t\u003cli\u003e\n\u003cu\u003e\u003cstrong\u003eMarkings: \u003c\/strong\u003e\u003c\/u\u003e significantly higher contrast, darker marks on both the bottom and top faces of our FIB ring (the double spot pattern at 12 o'clock is mirrored on the top and bottom), making orientation much easier.\u003c\/li\u003e\t\u003cli\u003e\n\u003cu\u003e\u003cstrong\u003eAngled Face\u003c\/strong\u003e\u003c\/u\u003e: instead of having one \"notch\" area that is cut out of the bottom, flat surface at an angle for shallow angled FIB milling, the entire bottom face of our FIB ring is angled. Functionally, FIB milling remains the same, but there is better beam access to the grid, resulting in a larger area of the grid available for milling - less \"lost\" area on the grid and more precious cells able to be imaged.\u003c\/li\u003e\t\u003cli\u003e\n\u003cu\u003e\u003cstrong\u003eSmall Notch on Inner Diameter\u003c\/strong\u003e\u003c\/u\u003e: this is used in our production process. It can be used for orienting the ring in the clipping station before the grid is placed, but is then covered by the grid (this is a secondary benefit - it's main use is just for our production)\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095489323259,"sku":"11011003","price":2500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-11011003.png?v=1786456256"},{"product_id":"100-pack-cryoarm-c-clips","title":"100-Pack, CryoARM C-Clips","description":"\u003cp\u003eNanoSoft's CryoARM c-clips are compatible with the JEOL cryoARM cartridge\/autoloader system. These c-clips have been tested and work seemlessly with the cryoARM cartridges, with the same level of robustness as the OEM version, at a much better price point. They can be used many times, with similar care as the OEM JEOL version, but at this price point, you can feel more comfortable using them fewer times, reducing risk of using old, damaged clips.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095489356027,"sku":"34011001","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-34011001-1-size.jpg?v=1786546758"},{"product_id":"cassette-tweezers","title":"Cassette Tweezers","description":"\u003cp\u003eCassette Tweezers for manipulation and maneuvering of the Thermo Fisher Scientific autoloader cassettes. Perform the same as the Thermo Fisher version, at a lower price.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095492829435,"sku":"31021001","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft_31021001-1.jpg?v=1786545416"},{"product_id":"100-pack-c-clips","title":"100-Pack, C-Clips","description":"\u003cp\u003eShips with 100 c-clips\u003c\/p\u003e\u003cp\u003eNanoSoft C-clips are high-quality, equivalent to the TFS version. Our c-clips are also compatible with TFS autogrid rings, and our autogrid rings are compatible with TFS c-clips. Our rings and c-clips are compatible with both NanoSoft and TFS clipping stations and tools.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095492862203,"sku":"11011002","price":200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_91181fb4eb764444b1bb301ed70284ad_mv2.jpg?v=1785154357"},{"product_id":"100-pack-autogrid-rings-c-clips","title":"100-Pack, Autogrid Rings \u0026 C-Clips","description":"\u003cp\u003eShips with 100 autogrid rings and 100 c-clips\u003c\/p\u003e\u003cp\u003eNanoSoft's Autogrid Rings (sometimes called c-clip rings) are a premium quality, less variable, functionally-equivalent option for clipping cryoEM grids for use in Thermo Fisher Scientific (TFS) cryoEMs and autoloader systems.  Our rings are half the price of the TFS version, providing high value for a one-time use consumable. Additionally, we offer a 10% discount for large volume orders (5,000+ rings) (please email us to setup the discount). They have been tested across 50+ cryoEM facilities\/labs (as of June 2023) without any instances of defects or issues in the autoloader or microscope.\u003c\/p\u003e\u003cp\u003eNanoSoft has conducted significant analysis and measurements on the TFS version of the rings to ensure that we can produce rings that are functionally-equivalent, in terms of both geometry and material. We are using cutting-edge manufacturing technology to produce a less variable autogrid ring than the TFS version (see data below). Data  from autogrids clipped with our rings has been processed and provided high quality results.\u003c\/p\u003e\u003cp\u003eNanoSoft C-clips are high-quality, equivalent to the TFS version. Our c-clips are also compatible with TFS autogrid rings, and our autogrid rings are compatible with TFS c-clips. Our rings and c-clips are compatible with both NanoSoft and TFS clipping stations and tools.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095492894971,"sku":"11011001","price":1000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_f6d78b2116f54ff0aa7e809b55957ddf_mv2.jpg?v=1785154357"},{"product_id":"mitegen-cassette-loading-station-insert","title":"MiTeGen Cassette Loading Station Insert","description":"\u003cp\u003eInsert for easy AutoGrid Cassette Puck use in the ThermoFisher Scientific Cassette Loading station.\u003c\/p\u003e","brand":"MiTeGen","offers":[{"title":"Default Title","offer_id":49095493255419,"sku":"28081022","price":511.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_e7c81c8ab11442319727dd6fb5bf9259_mv2.jpg?v=1785154357"},{"product_id":"cryo-em-autogrid-cassette-puck","title":"Cryo-EM Autogrid Cassette Puck","description":"\u003cp\u003e1 Autogrid Cassette Puck for storing Thermo Fisher autogrid cassette. NOTE: Insert for Thermo Fisher cassette transfer\/nanocab loading station is not included (though included in picture)\u003c\/p\u003e\u003cp\u003eThe new AutoGrid Cassette Storage and Shipping puck is based on our 2nd generation Cryo-EM Puck. The AutoGrid Cassette puck allows users to screen on a Glacios and ship the same AutoGrid cassette puck to a collection facility, or allow facilities to store their cassettes in the puck canes, etc. Designed to fit into cassette loading station.\u003c\/p\u003e\u003cp\u003eWorks with the following storage, shipping canes and tools:\u003c\/p\u003e\u003cul\u003e\t\u003cli\u003eHC34 and HC35 storage canes\u003c\/li\u003e\t\u003cli\u003ePuck shipping cane\u003c\/li\u003e\t\u003cli\u003eGrasping tongs\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"MiTeGen","offers":[{"title":"Default Title","offer_id":49095494467835,"sku":"28081009","price":699.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_4fb357e0165f4eb6b0decc3368907280_mv2.png?v=1785154392"},{"product_id":"clipping-station","title":"Clipping Station with Clipping Tools","description":"\u003cp\u003eIncluded in this SKU: Station Foam Dewar, Clipping Hub, Station Lid and Plug, 1 Clipping Tool Puck Rack, Silicone anti-rotation Mat, plus your selected bundle of 8 or 16 clipping tools\u003c\/p\u003e\u003cp\u003eAlready own clipping tools? The \u003ca href=\"\/products\/clipping-station-without-clipping-tools\"\u003eClipping Station without Clipping Tools\u003c\/a\u003e is the same station without a tool bundle.\u003c\/p\u003e\u003cp\u003eOur Clipping Station provides unmatched ease of use and efficiency for the clipping of cryoEM grids for Thermo Fisher autoloader-based microscopes, with its design optimized for the clipping workflow. A high quality foam dewar integrates grid box storage puck access directly adjacent to the clipping space, increasing ease of use and reducing the potential for contamination transferring grid boxes from pucks in other stations. A new clipping design makes the workflow easier, and a well designed lid balances ease of use and protection. Furthermore, our Clipping Station is compatible with both NanoSoft and Thermo Fisher clipping tools.\u003c\/p\u003e\u003cp\u003eThe station is housed in a high quality, closed-cell polyethylene foam, i.e. the Spearlab foam. The foam is highly durable and cools down and warms up\/dries off quickly. The inside of the foam dewar is designed to match the intricacies of the workflow; there are 3 cutout positions in the foam, each of which holds a component firmly in place such that it doesn't slide around during use. One cutout holds the clipping hub, which is the part used for clipping. The other 2 are the appropriate size to hold storage pucks. This allows you to place a storage puck directly and securely in the station adjacent to the Hub, so that grid boxes can be accessed without needing to transfer them through the ambient environment from another dewar. Furthermore, the Station comes with a puck sized holder for clipping tools, such that up to 33 tools can be pre-loaded with c-clips and placed in the holder to be cooled down while being held reliably in place; the puck and tools are in a position that is easy to access and enables seamless clipping of up to 33 samples at one time with one puck-full of tools. A valuable option is also to use the MiTeGen cassette puck - this enables you to load a cassette at the same time and in the same station where grids are clipped.\u003c\/p\u003e\u003cp\u003eThe Hub used for clipping utilizes a novel mechanism for moving the guidance cylinder, used to center the clipping tool over the autogrid ring, into and out of position. Instead of the rotating brass cylinder, which is often difficult to turn and can bend tweezers, the seesaw like mechanism requires the user to push down on either side of the cantilever beam to move the guidance cylinder into the position for clipping or into the position where the autogrid ring is placed or where the clipped grid can be picked up. Once the system and clipping tools are cooled down, and a storage puck placed into its spot adjacent to the Hub, the grid box holding the grids to be clipped can be moved to a grid box pocket in the Hub for easy grid access for clipping, and replacement of the autogrid after clipping.  Furthermore, The Hub has 4 \"on-deck\" positions for clipping tools where they can quickly be accessed for rapid-fire clipping. The shallow hole where the autogrid ring is placed for clipping has a dark colored surface to provide better contrast and easier tracking for placement of the autogrid ring and picking up of the clipped grid with autogrid tweezers. Furthermore, grooves are machined into the Hub to enable inspection of the clipped grid to ensure that it is well clipped and to roll the notch of cryoET, FIBSEM rings into the right orientation.\u003c\/p\u003e\u003cp\u003eThe lid for the station provides a thoughtful balance between usability and efficient separation of the clipping space from the ambient environment. The optimally designed opening in the lid provides the ideal amount of space to access the cantilever, the grid box pockets in the Hub and the 4 \"on-deck\" clipping tools, all without needing to rotate the lid, and while providing protection from ambient humidity. Knobs on the lid enable easy turning to access and transfer other grid boxes or clipping tools to the Hub, and a Lid insert can cover the entire opening so that the clipping space can be closed off from the ambient environment completely during cool down and as needed. Furthermore, a silicone sheet is provided upon which the entire station can be placed to reduce station movement when rotating the lid.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"With 8 Clipping Tools \/ With 2 Tweezers for Clipping Tool Handling","offer_id":49095495254267,"sku":"25011001","price":4350.0,"currency_code":"USD","in_stock":true},{"title":"With 16 Clipping Tools \/ Without Tweezers","offer_id":49095495287035,"sku":"25011001","price":5950.0,"currency_code":"USD","in_stock":true},{"title":"With 8 Clipping Tools \/ With Long Grid Tweezer and 2 Clipping Tool Tweezer","offer_id":49095495319803,"sku":"25011001","price":4415.0,"currency_code":"USD","in_stock":true},{"title":"With 8 Clipping Tools \/ Without Tweezers","offer_id":49095495352571,"sku":"25011001","price":4250.0,"currency_code":"USD","in_stock":true},{"title":"With 16 Clipping Tools \/ With Longer Tweezer for Grid Handling","offer_id":49095495385339,"sku":"25011001","price":6025.0,"currency_code":"USD","in_stock":true},{"title":"With 16 Clipping Tools \/ With Long Grid Tweezer and 2 Clipping Tool Tweezer","offer_id":49095495418107,"sku":"25011001","price":6115.0,"currency_code":"USD","in_stock":true},{"title":"With 16 Clipping Tools \/ With 2 Tweezers for Clipping Tool Handling","offer_id":49095495450875,"sku":"25011001","price":6050.0,"currency_code":"USD","in_stock":true},{"title":"With 8 Clipping Tools \/ With Longer Tweezer for Grid Handling","offer_id":49095495483643,"sku":"25011001","price":4325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-25011001-4.jpg?v=1785387081"},{"product_id":"clipping-tool-rack","title":"Clipping Tool Rack","description":"\u003cp\u003eThe Clipping Tool Rack holds 4 Clipping Tools for placement in the clipping station.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095495942395,"sku":"24031004","price":25.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-24031004-1_067c397e-29a7-4948-9589-2bc8f2960352.jpg?v=1784907160"},{"product_id":"c-clip-bottoming-tool","title":"C-Clip Bottoming Tool","description":"\u003cp\u003eThe C-clip Bottoming Tool provides an easier and more efficient way to \"bottom\" the C-clip at the tip of the barrel of a clipping tool prior to clipping. After pressing the c-clip into the barrel of the tool, instead of pressing the tip of the barrel against the tabletop or a pair of tweezers to push the c-clip to the tip of the barrel (by pressing the plunger), you place the barrel into the Bottoming Tool and press the plunger of the tool to bottom the c-clip. The cylinder of our Bottoming Tool ensures that the barrel of the clipping tool is straight, so upon pressing of the plunger to push the c-clip to the tip you are much less likely to \"mis-bottom\" the c-clip. Often when pressing the tip against the table top or another flat surface, you are not able to hold the barrel exactly straight again the surface and you the c-clip can fly out of the tool and is lost. Our Bottoming Tool provides an easy way to ensure you don't mis-bottom c-clips anymore. \u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095495975163,"sku":"24021001","price":40.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-24021001-1_6b4ecb92-0c1b-4de6-9589-4d1198a563f7.jpg?v=1784907159"},{"product_id":"clipping-tools-4-pack","title":"Clipping Tools, 4-Pack","description":"\u003cp\u003eA bundle including 4 Clipping Tools, 1 C-clip Bottoming Tool and 1 Clipping Tool Rack.\u003c\/p\u003e\u003cp\u003eOur Clipping Tool is loaded with c-clips and clips grids the same way as the Thermo Fisher version, and is compatible with the Thermo Fisher clipping station. The difference is that with our version, instead of ejecting the C-clip by pressing a long plastic handle like with the Thermo version, you press on our tool with a pair of tweezers. Our version has the advantage of a compact design so that when they are placed in LN2 in the clipping station to be cooled down, the entire body is deep enough inside the station that they are untouched by any frost from environmental moisture, even when left in the station at cryogenic temperature for long periods of time. This means you can pre-load as many of our tools with C-clips as you would like, cool them all down at the same time, and then clip all your grids at one time without with little consideration for ice contamination - no need to warm, re-load and re-cool clipping tools. \u003c\/p\u003e\u003cp\u003eOur recommended workflow is that after loading the Clipping Tools with c-clips, you place them into our Clipping Tool Rack, and then place the rack with Clipping Tools into the clipping station for cooling. When ready to clip, you can use any type of tweezer to grab the back end of the Clipping Tool - the square profile of the plunger\/back end enables simple and comfortable grasping with tweezer tips. Small protuberances provide extra support to keep the Clipping Tool from twisting while you transfer it from the rack to the position to clip the grid. We recommend using our Reverse Action Autogrid Tweezers - the Clipping Tools remains very securely in position during the transfer. Place the Clipping Tool into position for clipping and release the tool; we recommend pressing down on the top of the Clipping Tool to eject the c-clip and clip the grid, i.e. not while grasping the sides of the plunger with the tweezers. This will help you ensure that you can keep the tweezers straight while pressing the plunger - you will find that the shorter body of our Clipping Tool enables you to keep the tool straighter than competitor clipping tools while clipping, which helps ensure that c-clip actually insert into the autogrid ring as intended.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095496007931,"sku":"24011001","price":900.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-24011001-1_6f7effaf-f988-4109-a735-16328e4d26fa.jpg?v=1784907159"},{"product_id":"clipping-tool","title":"Clipping Tool","description":"\u003cp\u003eOur Clipping Tool is loaded with c-clips and clips grids the same way as the Thermo Fisher version, and is compatible with the Thermo Fisher clipping station. The difference is that with our version, instead of ejecting the C-clip by pressing a long plastic handle like with the Thermo version, you press on our tool with a pair of tweezers. Our version has the advantage of a compact design so that when they are placed in LN2 in the clipping station to be cooled down, the entire body is deep enough inside the station that they are untouched by any frost from environmental moisture, even when left in the station at cryogenic temperature for long periods of time. This means you can pre-load as many of our tools with C-clips as you would like, cool them all down at the same time, and then clip all your grids at one time without with little consideration for ice contamination - no need to warm, re-load and re-cool clipping tools. \u003c\/p\u003e\u003cp\u003eOur recommended workflow is that after loading the Clipping Tools with c-clips, you place them into our Clipping Tool Rack, and then place the rack with Clipping Tools into the clipping station for cooling. When ready to clip, you can use any type of tweezer to grab the back end of the Clipping Tool - the square profile of the plunger\/back end enables simple and comfortable grasping with tweezer tips. Small protuberances provide extra support to keep the Clipping Tool from twisting while you transfer it from the rack to the position to clip the grid. We recommend using our Reverse Action Autogrid Tweezers - the Clipping Tools remains very securely in position during the transfer. Place the Clipping Tool into position for clipping and release the tool; we recommend pressing down on the top of the Clipping Tool to eject the c-clip and clip the grid, i.e. not while grasping the sides of the plunger with the tweezers. This will help you ensure that you can keep the tweezers straight while pressing the plunger - you will find that the shorter body of our Clipping Tool enables you to keep the tool straighter than competitor clipping tools while clipping, which helps ensure that c-clip actually insert into the autogrid ring as intended.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095496040699,"sku":"24021002","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-24021002_0c6df87d-65dc-4a57-ba49-ad23e17cc920.jpg?v=1784907159"},{"product_id":"reverse-action-autogrid-tweezer","title":"Reverse Action Autogrid Tweezer","description":"\u003cp\u003eNanoSoft has developed a version of the Autogrid Tweezers that maintains the same tip geometry as the traditional Autogrid Tweezers (with notched tip to safely cradle autogrids and ensuring that autogrids are placed centered in the cassette slot and at the correct depth), but with a reverse-action handle. The reverse-action handle ensures that the tweezers hold the autogrid securely in their natural state, making orientation and manipulation steps with the autogrid easier, and ensuring that the valuable clipped grid cannot be dropped.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095496139003,"sku":"23021004","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-RAAGT.jpg?v=1786644292"},{"product_id":"autogrid-tweezer","title":"Autogrid Tweezer","description":"\u003cp\u003eNanoSoft offers the Autogrid Tweezers that accompany the autogrid clipping and cassette loading station from Thermo Fisher Scientific for their autoloader-based cryo-EM workflow.  Our Autogrid Tweezers are designed to have the same geometry as the version from Thermo Fisher, such that cartridges\/autogrids are handled and loaded into the cassette in the same way. This includes a notched feature in the tip of the tweezers that provides a datum against which the autogrid can rest, ensuring that the autogrid is placed centered in the cassette slot and at the correct depth. \u003c\/p\u003e\u003cp\u003eFurthermore, our version of the Autogrid Tweezers has the removable tips attached with a specialty adhesive that ensures that the tips remain aligned appropriately (while allowing for disassembly if needed).  We offer this item with equal or better performance than the Thermo Fisher part, but at a far more generous price. \u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095496630523,"sku":"23021002","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-AGT.jpg?v=1786643526"},{"product_id":"autogrid-inspection-tool","title":"Autogrid Inspection Tool","description":"\u003cp\u003eHigh demand for cryo-EM imaging time at core facilities has resulted in ever-growing throughput of samples through high-end, autoloader-based EM's.  Often the person loading autogrids into the autoloader cassette did not clip the grids that they are loading.  Inserting a poorly clipped autogrid into the cassette could lead to it popping out of the cassette while in the autoloader and significant EM downtime.\u003c\/p\u003e\u003cp\u003eThe autogrid inspection tool is a low-cost way of performing a last autogrid inspection step prior to loading them into the cassette.  It is placed into a grid box spot in the cassette loading station and will remain there securely due to the spring-loaded detent on the side of the tool.  Autogrids can be placed in the groove of the Autogrid inspection tool and quickly flipped back and forth to check that the grid is securely clipped.  It provides a final, low-cost check to help ensure only well-clipped grids are loaded into the autoloader, saving the potential disaster of a poorly clipped grid coming undone in the autoloader and weeks of downtime.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095497482491,"sku":"18021002","price":95.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-18021002_5975c3be-7a76-459a-afe2-f4ca0125f54f.jpg?v=1784907071"},{"product_id":"insulated-autogrid-tweezer","title":"Insulated Autogrid Tweezer","description":"\u003cp\u003eNanoSoft offers the Autogrid Tweezers that accompany the autogrid clipping and cassette loading station from Thermo Fisher Scientific for their autoloader-based cryo-EM workflow.  Our Autogrid Tweezers are designed to have the same geometry as the version from Thermo Fisher, such that cartridges\/autogrids are handled and loaded into the cassette in the same way. This includes a notched feature in the tip of the tweezers that provides a datum against which the autogrid can rest, ensuring that the autogrid is placed centered in the cassette slot and at the correct depth. \u003c\/p\u003e\u003cp\u003eFurthermore, our version of the Autogrid Tweezers has the removable tips attached with a specialty adhesive that ensures that the tips remain aligned appropriately (while allowing for disassembly if needed).  We offer this item with equal or better performance than the Thermo Fisher part, but at a far more generous price. \u003c\/p\u003e\u003cp\u003eThis insulated version is finished with a color-coded insulating coating on the arms, available in white, black, blue, green, yellow, and red — useful for keeping tweezers visually assigned to a specific instrument, workflow, or user. Tip geometry and the removable-tip design are identical to the standard \u003ca href=\"\/products\/autogrid-tweezer\"\u003eAutogrid Tweezer\u003c\/a\u003e.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"White","offer_id":49285183930619,"sku":"23011002","price":435.0,"currency_code":"USD","in_stock":true},{"title":"Black","offer_id":49285190385915,"sku":"23011003","price":435.0,"currency_code":"USD","in_stock":true},{"title":"Blue","offer_id":49285190418683,"sku":"23011007","price":435.0,"currency_code":"USD","in_stock":true},{"title":"Green","offer_id":49285190451451,"sku":"23011004","price":435.0,"currency_code":"USD","in_stock":true},{"title":"Yellow","offer_id":49285190484219,"sku":"23011005","price":435.0,"currency_code":"USD","in_stock":true},{"title":"Red","offer_id":49285190516987,"sku":"23011006","price":435.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-AGT_WHITE_6efcb1e6-94de-4654-a5d7-2ae0a86b3b1a.jpg?v=1788962093"},{"product_id":"clipping-station-without-clipping-tools","title":"Clipping Station without Clipping Tools","description":"\u003cp\u003eIncluded in this SKU: Station Foam Dewar, Clipping Hub, Station Lid and Plug, 1 Clipping Tool Puck Rack, Silicone anti-rotation Mat\u003c\/p\u003e\u003cp\u003eThis configuration ships without clipping tools, for labs that already own NanoSoft or Thermo Fisher tools. If you would like tools included, see the \u003ca href=\"\/products\/clipping-station\"\u003eClipping Station with Clipping Tools\u003c\/a\u003e, available with 8 or 16 tools.\u003c\/p\u003e\u003cp\u003eOur Clipping Station provides unmatched ease of use and efficiency for the clipping of cryoEM grids for Thermo Fisher autoloader-based microscopes, with its design optimized for the clipping workflow. A high quality foam dewar integrates grid box storage puck access directly adjacent to the clipping space, increasing ease of use and reducing the potential for contamination transferring grid boxes from pucks in other stations. A new clipping design makes the workflow easier, and a well designed lid balances ease of use and protection. Furthermore, our Clipping Station is compatible with both NanoSoft and Thermo Fisher clipping tools.\u003c\/p\u003e\u003cp\u003eThe station is housed in a high quality, closed-cell polyethylene foam, i.e. the Spearlab foam. The foam is highly durable and cools down and warms up\/dries off quickly. The inside of the foam dewar is designed to match the intricacies of the workflow; there are 3 cutout positions in the foam, each of which holds a component firmly in place such that it doesn't slide around during use. One cutout holds the clipping hub, which is the part used for clipping. The other 2 are the appropriate size to hold storage pucks. This allows you to place a storage puck directly and securely in the station adjacent to the Hub, so that grid boxes can be accessed without needing to transfer them through the ambient environment from another dewar. Furthermore, the Station comes with a puck sized holder for clipping tools, such that up to 33 tools can be pre-loaded with c-clips and placed in the holder to be cooled down while being held reliably in place; the puck and tools are in a position that is easy to access and enables seamless clipping of up to 33 samples at one time with one puck-full of tools. A valuable option is also to use the MiTeGen cassette puck - this enables you to load a cassette at the same time and in the same station where grids are clipped.\u003c\/p\u003e\u003cp\u003eThe Hub used for clipping utilizes a novel mechanism for moving the guidance cylinder, used to center the clipping tool over the autogrid ring, into and out of position. Instead of the rotating brass cylinder, which is often difficult to turn and can bend tweezers, the seesaw like mechanism requires the user to push down on either side of the cantilever beam to move the guidance cylinder into the position for clipping or into the position where the autogrid ring is placed or where the clipped grid can be picked up. Once the system and clipping tools are cooled down, and a storage puck placed into its spot adjacent to the Hub, the grid box holding the grids to be clipped can be moved to a grid box pocket in the Hub for easy grid access for clipping, and replacement of the autogrid after clipping.  Furthermore, The Hub has 4 \"on-deck\" positions for clipping tools where they can quickly be accessed for rapid-fire clipping. The shallow hole where the autogrid ring is placed for clipping has a dark colored surface to provide better contrast and easier tracking for placement of the autogrid ring and picking up of the clipped grid with autogrid tweezers. Furthermore, grooves are machined into the Hub to enable inspection of the clipped grid to ensure that it is well clipped and to roll the notch of cryoET, FIBSEM rings into the right orientation.\u003c\/p\u003e\u003cp\u003eThe lid for the station provides a thoughtful balance between usability and efficient separation of the clipping space from the ambient environment. The optimally designed opening in the lid provides the ideal amount of space to access the cantilever, the grid box pockets in the Hub and the 4 \"on-deck\" clipping tools, all without needing to rotate the lid, and while providing protection from ambient humidity. Knobs on the lid enable easy turning to access and transfer other grid boxes or clipping tools to the Hub, and a Lid insert can cover the entire opening so that the clipping space can be closed off from the ambient environment completely during cool down and as needed. Furthermore, a silicone sheet is provided upon which the entire station can be placed to reduce station movement when rotating the lid.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"With 2 Tweezers for Clipping Tool Handling","offer_id":49285247467771,"sku":"25011001","price":2650.0,"currency_code":"USD","in_stock":true},{"title":"Without Tweezers","offer_id":49285248057595,"sku":"25011001","price":2550.0,"currency_code":"USD","in_stock":true},{"title":"With Long Grid Tweezer and 2 Clipping Tool Tweezer","offer_id":49285248090363,"sku":"25011001","price":2715.0,"currency_code":"USD","in_stock":true},{"title":"With Longer Tweezer for Grid Handling","offer_id":49285248123131,"sku":"25011001","price":2625.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-25011001-2_a35511db-9fe0-4df4-a44a-be83ae73e128.jpg?v=1788964516"},{"product_id":"thermo-fisher-cassette-loading-station-repair-1","title":"Thermo Fisher Cassette Loading Station Repair","description":"\u003cp\u003eThe internal plastic insert from Thermo Fisher's cassette loading station, which contains the metal cassette holder where autogrids are loaded, is very prone to cracking. Rather than purchase a brand new loading station, use NanoSoft's Cassette Loading Station Repair Service. We'll replace the plastic insert with our brand new insert with improved design and material, leading to a more durable part that will last longer.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49322686185723,"sku":"41041001","price":1400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-20011001-5.jpg?v=1784905665"},{"product_id":"insulated-reverse-action-autogrid-tweezer","title":"Insulated Reverse Action Autogrid Tweezer","description":"\u003cp\u003eNanoSoft has developed a version of the Autogrid Tweezers that maintains the same tip geometry as the traditional Autogrid Tweezers (with notched tip to safely cradle autogrids and ensuring that autogrids are placed centered in the cassette slot and at the correct depth), but with a reverse-action handle. The reverse-action handle ensures that the tweezers hold the autogrid securely in their natural state, making orientation and manipulation steps with the autogrid easier, and ensuring that the valuable clipped grid cannot be dropped.\u003c\/p\u003e\n\u003cp\u003eThis insulated version is finished with a color-coded insulating coating on the arms, available in white, black, blue, green, yellow, and red — useful for keeping tweezers visually assigned to a specific instrument, workflow, or user. Tip geometry and the removable-tip design are identical to the standard \u003ca href=\"\/products\/autogrid-tweezer\"\u003eAutogrid Tweezer\u003c\/a\u003e.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Blue","offer_id":49328690135291,"sku":"23011013","price":435.0,"currency_code":"USD","in_stock":true},{"title":"Green","offer_id":49328690168059,"sku":"23011010","price":435.0,"currency_code":"USD","in_stock":true},{"title":"Black","offer_id":49328690200827,"sku":"23011009","price":435.0,"currency_code":"USD","in_stock":true},{"title":"White","offer_id":49328690233595,"sku":"23011008","price":435.0,"currency_code":"USD","in_stock":true},{"title":"Yellow","offer_id":49328690266363,"sku":"23011011","price":435.0,"currency_code":"USD","in_stock":true},{"title":"Red","offer_id":49328690299131,"sku":"23011012","price":435.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-RAAGT_BLUE.jpg?v=1786644292"},{"product_id":"critical-sample-insert-for-clipping-station","title":"Insert (TFS Hub Compatible) - NanoSoft Clipping Station","description":"\u003cp\u003eThis plastic insert fits into the NanoSoft Clipping Station to expand the functionality of the station. First, the insert has features to hold the NanoSoft Clipping Hub and a puck, but can also hold the rotating clipping hub from the Thermo Fisher clipping station, making the NanoSoft dewar compatible with the Thermo hub. Furthermore, this insert is made from a sterilize-able plastic. If you're clipping a sample that is considered a biological risk, clipping can be done with this insert in place, containing the sample and LN2 in the insert which can be sterilized by autoclave, bleach, etc. Furthermore, if you need perfectly still LN2 for the clipping of a particularly sensitive sample, the LN2 between the inside foam wall of the Clipping Station and the insert result in ultra-still LN2 inside the insert where clipping is performed. \u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49329682579707,"sku":"25021005","price":1800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/CriticalSampleInsertinStation2.jpg?v=1789671393"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/collections\/Clipping_White_noBR_horizPadding.svg?v=1785868625","url":"https:\/\/nanosoftcryo.com\/collections\/clipping-tools.oembed","provider":"NanoSoft","version":"1.0","type":"link"}