{"title":"Vitrification","description":"\u003cp\u003eTools that improve cryo-EM plunge freezing and vitrification — Vitrobot-compatible dewars and metal parts, ethane cups, condensers, blotting paper and more.\u003c\/p\u003e","products":[{"product_id":"blotting-paper-leica-em-gp2","title":"Blotting Paper, Leica EM GP2","description":"\u003cp\u003eStandard blotting filter paper for the Leica EM GP2 Plunge Freezer.\u003c\/p\u003e\u003cp\u003eØ55\/15mm, Grade 595\u003c\/p\u003e","brand":"Ted Pella","offers":[{"title":"Default Title","offer_id":49095464517883,"sku":"28011013","price":49.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_97331f20729d4355a6f9c3deb73ecf7a_mv2_38abb709-c27a-4598-9759-0dff13b97adf.jpg?v=1785154265"},{"product_id":"blotting-paper-vitrobot","title":"Blotting Paper, Vitrobot","description":"\u003cp\u003eStandard blotting filter paper for the Thermo Fisher\/FEI Vitrobot Plunge Freezer.\u003c\/p\u003e\u003cp\u003eØ55\/20mm, Grade 595\u003c\/p\u003e","brand":"Ted Pella","offers":[{"title":"Default Title","offer_id":49095464550651,"sku":"28011014","price":49.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_97331f20729d4355a6f9c3deb73ecf7a_mv2.jpg?v=1785154265"},{"product_id":"standard-gravitri-plunge-cooler","title":"Standard GraVitri Plunge Cooler","description":"\u003cp\u003eMiTeGen's Standard GraVitri Plunge Cooler is a reliable plunge cooler that  will dependably provide fast plunge speeds without risk of grid or tweezer damage, and a humidified environment that precludes excess sample drying. Building on the Basic Model, this design balances user friendliness, ergonomics function, and cost to deliver an affordable system with superior capabilities. See images for everything included.\u003c\/p\u003e\u003cp\u003eMiTeGen's GraVitri Plunge Cooler series provides consistent vitrification quality required for high-end structural techniques, proven by successful data collection across Single Particle Analysis (SPA), Cryogenic Electron Tomography (Cryo-ET) and Microcrystal Electron Diffraction (MicroED). Built on a Time-Tested Design developed in collaboration with the MRC LMB and Dr. Christopher Russo, this cooler has reliably enabled researchers worldwide to vitrify thousands of cryo-EM grids for high-resolution data collection.\u003c\/p\u003e\u003cp\u003eThe GraVitri Series features an advanced modular design, allowing your initial investment to easily grow and evolve with the changing scope of your cryo-EM research. By simply integrating new modules and accessories, you can precisely configure the system to meet specialized experimental needs without replacing the core unit. From custom enclosures for hands-on humidified sample prep to temperature-controlled enclosures, we can engineer solutions for your lab.\u003c\/p\u003e","brand":"MiTeGen","offers":[{"title":"Default Title","offer_id":49095468155131,"sku":null,"price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_aca6d5fa390349dfa3db52892dadbea4_mv2.jpg?v=1785154265"},{"product_id":"grid-box-ring-for-anti-contamination-grid-box","title":"Grid Box Ring for Anti-Contamination Grid Box","description":"\u003cp\u003eA grid box ring for the Vitrobot to enable an Anti-Contamination Grid Box to be held in place by screwing down a pin lid, so that the individual magnetic pocket lids can be placed and removed without disturbing the grid box.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095468417275,"sku":"21021008","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-21021008.jpg?v=1785444973"},{"product_id":"basic-gravitri-plunge-cooler","title":"Basic GraVitri Plunge Cooler","description":"\u003cp\u003eMiTeGen's Basic GraVitri Plunge Cooler is a reliable plunge cooler that  will dependably provide fast plunge speeds without risk of grid or tweezer damage, and is made with budget in mind. See images for everything included.\u003c\/p\u003e\u003cp\u003eMiTeGen's GraVitri Plunge Cooler series provides consistent vitrification quality required for high-end structural techniques, proven by successful data collection across Single Particle Analysis (SPA), Cryogenic Electron Tomography (Cryo-ET) and Microcrystal Electron Diffraction (MicroED). Built on a Time-Tested Design developed in collaboration with the MRC LMB and Dr. Christopher Russo, this cooler has reliably enabled researchers worldwide to vitrify thousands of cryo-EM grids for high-resolution data collection.\u003c\/p\u003e\u003cp\u003eThe GraVitri Series features an advanced modular design, allowing your initial investment to easily grow and evolve with the changing scope of your cryo-EM research. By simply integrating new modules and accessories, you can precisely configure the system to meet specialized experimental needs without replacing the core unit. From custom enclosures for hands-on humidified sample prep to temperature-controlled enclosures, we can engineer solutions for your lab.\u003c\/p\u003e","brand":"MiTeGen","offers":[{"title":"Default Title","offer_id":49095468482811,"sku":null,"price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_617deb33590a4b7f85adfed84a4e5d25_mv2.jpg?v=1785154266"},{"product_id":"leica-em-gp2-larger-grid-box-container","title":"Leica GP2 – Grid Box Container","description":"\u003cp\u003eThe grid box holder for the Leica EM GP2 has a pocket for a grid box that is very shallow, which has minimal grasp on grid boxes under LN2 and leads to the grid box easily coming out of position. NanoSoft's larger grid box holder has a deeper pocket (same depth as grid box pockets in other NanoSoft or Thermo Fisher workstations), resulting in more reliable grid box containment in the station.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095469990139,"sku":"39011001","price":160.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-39011001-1.jpg?v=1785445793"},{"product_id":"ethane-temperature-controlled-vitrobot-dewar","title":"Ethane Temperature Controlled Vitrobot Dewar","description":"\u003cp\u003eDownload a PDF of our Quick Start Guide for the Ethane-Temperature Controlled Dewar \u003cu\u003e\u003ca href=\"http:\/\/www.nanosoftmaterials.com\/startguide-tempcontrolleddewar\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/u\u003e\u003c\/p\u003e\u003cp\u003eOur Ethane-Temperature Controlled Vitrobot Dewar enables control of the temperature of your liquid ethane for plunge freezing. Furthermore, the control box where the temperature is monitored and controlled also includes a tool warmer pad, with a warming plate and air flow to dry your cryo-tools quicker during vitrification.\u003c\/p\u003e\u003cp\u003eCryoEM practictioners have always relied on very rough control of the ethane temperature during vitrification. Usually, people wait until there is a bit of ethane ice on the wall of the brass cup, or until the ethane looks milky, to plunge their sample. Though not very repeatable, it often does the job, and the thought was always that colder ethane was better.\u003c\/p\u003e\u003cp\u003eMore recently findings suggest that colder ethane is not always better. Furthermore, with the lack of consistency in cryoEM sample preparation, more control over protocol variables can only help. Our Ethane-Temperature Controlled Dewar has sensors and heaters built into the brass ethane cup such that the temperature of the ethane can be controlled accurately and precisely, providing reliability and consistency in one more variable in your cryoEM sample preparation process. Finally you can accurately control your ethane temperature, especially away from the melting point of the ethane, where you cannot physically tell the temperature of the ethane (with frost or \"milkiness\").\u003c\/p\u003e\u003cp\u003eThe benefits of our system include:\u003c\/p\u003e\u003cul\u003e\t\u003cli\u003eAccurate control of the ethane temperature through embedded heaters and sensors\u003c\/li\u003e\t\u003cli\u003eA \"Snowflake Setting\"that will reliably keep the ethane temperature such that there is just a crust of frozen ethane on the cup\u003c\/li\u003e\t\u003cli\u003eHigh quality, robust foam dewar and cryogenically-compatible plastic basin\u003c\/li\u003e\t\u003cli\u003eRobust construction, whereby the brass cup, plastic basin and foam dewar can be disassembled without any tools for drying\u003c\/li\u003e\t\u003cli\u003eThe control provides a bake out cycle to quickly warm up the ethane cup and accelerate drying of the entire dewar assembly\u003c\/li\u003e\t\u003cli\u003eA  high quality, OLED screen with knob for easy system operation\u003c\/li\u003e\t\u003cli\u003eTool warmer built into the control box for convenient warming and drying of your tools.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095490470139,"sku":"26021004","price":7500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-26021004-1.jpg?v=1786545758"},{"product_id":"vitrification-foam-dewar","title":"Vitrification Foam Dewar","description":"\u003cp\u003eNanoSoft's foam Vitrification Dewar is compatible with the Vitrobot, and can also provide a robust and easy option for custom, home-made cryoEM sample preparation systems. Furthermore, our parts are interchangeable with FEI parts, i.e. our foam dewar works with FEI metal parts and our metal parts work with the FEI foam dewar. Our foam dewar, developed in collaboration with Spearlab (patent # 7,971,744), provides a well-priced, easy to acquire, robust dewar for cryoEM sample preparation. The design provides an improved interface, such that the Igloo creates a better seal on our dewar containing boiled, cold nitrogen gas in the head space above the dewar allowing for safer grid transfer to the grid box.\u003c\/p\u003e\u003cp\u003eThis listing is for the foam dewar on its own. For the dewar bundled together with the matching metal parts set, see the \u003ca href=\"\/products\/vitrification-foam-dewar-with-metal-parts\"\u003eVitrification Foam Dewar with Metal Parts\u003c\/a\u003e.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095490896123,"sku":"21021005","price":475.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-21021005_34940060-7a31-407e-ac95-dfcacc01d1e6.jpg?v=1784907160"},{"product_id":"cryo-em-grid-box-tweezers","title":"CryoEM Grid Box Tweezers","description":"\u003cp\u003eSimplify cryo grid box handling with these easy-to-use tweezers. Specially designed to grip the box’s central screw, rather than its sides.\u003c\/p\u003e","brand":"EMTec","offers":[{"title":"Default Title","offer_id":49095494172923,"sku":"28081010","price":50.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_b2ef95e48fc74cbdbe676a78e2b8482b_mv2.jpg?v=1785154391"},{"product_id":"pin-lid-tool","title":"Pin Lid Tool","description":"\u003cp\u003eOur Pin Lid Manipulator Tool provides a much more robust hold on a pin lid than other competitor tools. The tip of our tool has slots on either side, so that when you press the tool down onto the pin lid there is some flex in the tip of our tool, providing a tighter grip on the pin lid. Finally a pin lid manipulator tool that doesn't freeze your fingers, unscrew when manipulating the pin lid or require you to press down so hard on the pin lid that it cracks.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095495647483,"sku":"27011001","price":185.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-27011001_868727a8-ae68-4c3c-a044-f4aa84b26559.jpg?v=1784906979"},{"product_id":"foam-ring","title":"Foam Ring","description":"\u003cp\u003eFoam ring compatible with either the NanoSoft Vitrification Dewar or with Thermo Fisher Scientific's\/FEI's Vitrobot Dewar\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095496368379,"sku":"21141002","price":150.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-21141002_77d379b3-3a2b-41d0-9297-61e03479c573.jpg?v=1784907072"},{"product_id":"quick-lid","title":"Quick Lid","description":"\u003cp\u003eNanoSoft's Quick Lid is a simple way to protect already vitrified samples, which are sitting in a grid box waiting for a sample vitrification session to be completed, from ice particulate and other contamination that builds up in the Vitrobot dewar during sample preparation. When placed on top of a grid box, the Quick Lid acts like a shield keeping contamination out of the pockets of the grid box. The weight of the stainless steel Quick Lid keeps it in place on the grid box, reliably protecting grids from contamination. The bottom side of the lid has a small nub that easily fits into the center hole of the grid box, keeping it in place when positioned on the grid box, while being small enough to be easily placed. The top of the Quick Lid has a shaped pin that allows for easy transfer of the lid with any type of tweezers. Simply cool the Quick Lid in liquid nitrogen before placing on the grid box. When a sample is ready to be placed in the grid box, place the Quick Lid in one of the empty grid box positions in the aluminum ring (keeping it under liquid nitrogen) and replace it after the grid is positioned.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095496433915,"sku":"14011001","price":25.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-14011001-1_ed8c0a1e-b1f8-4eca-8d9f-acab54cc95f5.jpg?v=1784907159"},{"product_id":"ethane-cup","title":"Ethane Cup","description":"\u003cp\u003eEthane Cup with design that mimics that of the ethane cup from the Thermo Fisher Vitrobot dewar set. It works seamlessly with both the NanoSoft Vitrification Dewar or the styrofoam dewar from the Vitrobot, and is also compatible with the metal parts from NanoSoft or Thermo.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095496859899,"sku":"21031002","price":125.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-21031002_971b05ee-02b9-490d-84b9-6326bcb57bdd.jpg?v=1784907072"},{"product_id":"spider","title":"Spider","description":"\u003cp\u003eSpider with design that mimics that of the spider from the Thermo Fisher Vitrobot dewar set. It works seamlessly with both the NanoSoft Vitrification Dewar or the styrofoam dewar from the Vitrobot, and is also compatible with the metal parts from NanoSoft or Thermo.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095497122043,"sku":"21021001","price":200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-21021001_f25228b8-d393-4782-9d21-2a574011ce28.jpg?v=1784907072"},{"product_id":"grid-box-ring","title":"Grid Box Ring","description":"\u003cp\u003eGrid Box Ring with design that mimics that of the Grid Box Ring from the Thermo Fisher Vitrobot dewar set. It works seamlessly with both the NanoSoft Vitrification Dewar or the styrofoam dewar from the Vitrobot, and is also compatible with the metal parts from NanoSoft or Thermo.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095497154811,"sku":"21021002","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-21021002_790c30eb-867d-4f52-ba3a-b0e26b2169a5.jpg?v=1784907073"},{"product_id":"metal-part-set-vitrification-dewar","title":"Metal Part Set, Vitrification Dewar","description":"\u003cp\u003eSet of the 3 metal parts with designs that mimics those of the parts from the Thermo Fisher Vitrobot dewar set, work seamlessly with the NanoSoft or Thermo Vitrobot dewar with equal performance.\u003c\/p\u003e\u003cp\u003eOur Grid Box Ring sits at the same height as the Vitrobot version (so grid boxes sit at same depth into dewar) but is slightly thicker and remains in contact with liquid nitrogen longer if the nitrogen level gets low.  Our ethane cup dimensions mimic those of the Vitrobot ethane cup, and the spider as well. We offer these parts that perform just as well with the Vitrobot, but at a more generous price than other options. \u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095497187579,"sku":"21021003","price":525.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-21021003_09fc9446-6b1d-4bc6-990e-5720e69c6ec5.jpg?v=1784907072"},{"product_id":"ethane-condenser","title":"Ethane Condenser","description":"\u003cp\u003eEthane condensing with the FEI\/Thermo Fisher Vitrobot requires the user to manually place the tip of the nozzle from the ethane cylinder (e.g. pipette tip, bike pump needle, etc.) into the bottom corner of the brass ethane cup.  The user handles the nozzle with one hand and must simultaneously control ethane flow rate with the other hand (e.g. with needle valve), while watching the liquid ethane level.  The user will also often move the nozzle around the brass cup to avoid condensing ethane in a warmed position.\u003c\/p\u003e\u003cp\u003eNanoSoft's custom designed ethane condenser tightly interfaces with the spider from the FEI\/Thermo Fisher styrofoam dewar set.  The user places the spider normally and inserts the condenser.  The user does not need to handle an ethane nozzle and can instead focus solely on the liquid ethane level, using just one hand to control ethane flow rate, making the process much easier and ergonomic. Furthermore the condenser should reduce wasted ethane gas and the time required to fill the cup with liquid ethane.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095497253115,"sku":"16021002","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-16021002_1f0b9299-a38b-46a7-a088-e80cb050dc24.jpg?v=1784906980"},{"product_id":"igloo","title":"Igloo","description":"\u003cp\u003eA large number of variables influence blotting-based Cryo-EM sample preparation, which can lead to poor repeatability in sample quality.  The manual transfer of vitrified samples to the grid box is a critical time during which the sample is influenced by the ambient environment and by the expertise of the user.  The grid is exposed to air during the transfer - users report that they observe variations in sample quality based on time of year, weather, location, etc., which suggests ambient properties are influencing the sample.  Manually transferring the grid requires dexterity while simultaneously tending to multiple things (liquid nitrogen levels, ethane quality, etc.) – it’s stressful for experienced users, and for beginners trashed grids are the norm.\u003c\/p\u003e\u003cp\u003eNanoSoft's Igloo aims to better control the manual transfer when preparing samples with the Thermo Fisher Vitrobot.  A more enclosed environment provides protection from contaminating ambient humidity, while various system features transform the manual transfer process into a user friendly experience. The Igloo is beneficial for all users, but less experienced users in particular will be able to prepare viable grids sooner.\u003c\/p\u003e\u003cp\u003eIgloo Cover: The styrofoam ring from the Vitrobot dewar aims to maintain an environment containing cold, dry nitrogen gas above the liquid nitrogen to protect vitrified grids during their transfer.  However, the ring is open and susceptible to humidity in the external environment.  Furthermore, the ring is cold and collects ice.  As it is submerged into the liquid nitrogen with every plunge of the Vitrobot, ice particulate is deposited into the liquid nitrogen, which can contaminate grids already placed in the grid box.\u003c\/p\u003e\u003cp\u003eThe Igloo is a nearly enclosed cover that sits atop the Vitrobot dewar, with an opening large enough for comfortable grid button access and grid transfer.  The volume enclosed by the Igloo fills with cold gaseous nitrogen, creating a dry space with improved protection versus the ambient environment.  The Igloo is designed to fit comfortably over the floating styrofoam ring, minimizing the time that the styrofoam ring is exposed to ambient humidity and significantly reducing the potential for ice particulate contaminating the liquid nitrogen.  The Igloo material is compatible with liquid nitrogen temperatures, allowing for easy refill with the Igloo on the dewar.  Furthermore, the top surface of the Igloo remains comfortable to the touch, providing a convenient surface upon which the user can rest their hands for steady transfer.\u003c\/p\u003e\u003cp\u003eThe Cobra: Upon removing the tweezers from the Vitrobot dovetail, users must carefully hold the tweezers closed (to hold grid), keep the tips of the tweezers submerged in liquid ethane and simultaneously lift the dewar to transfer it away from the Vitrobot to transfer the sample to the grid box. \u003c\/p\u003e\u003cp\u003eThe Cobra is integrated into the top surface of the Igloo and flips up to provide a slot into which tweezers can be placed.  When resting in the slot, the tips of the tweezers remain submerged in liquid ethane.  The Cobra slot is compatible with both NanoSoft's Cryo-Tweezers and other Vitrobot tweezers.  The Cobra engages with magnets in the Plunge-Clamp of NanoSoft's Cryo-Tweezers, providing a more secure attachment. The Cobra provides freedom to the user to focus both hands on holding the dewar when moving it from the Vitrobot, the ability to fill the dewar with liquid nitrogen, etc.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095497810171,"sku":"19011001","price":1095.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-19011001-3.jpg?v=1785446743"},{"product_id":"cryo-tweezers","title":"Cryo-Tweezers","description":"\u003cp\u003eTweezers for plunge-freezing cryo-TEM sample preparation systems have remained the same across all platforms and generations.  Fighting to get the tweezer dovetail on and off of the plunger - and  fighting with a plastic \"O-ring\" to grasp and release the delicate TEM grid.  NanoSoft's Cryo-Tweezers work with all generations of the FEI Vitrobot and offer multiple features that make the sample preparation process more dependable and effortless for the user.  Experienced sample preparation experts will find it a smoother process.  Early experiences for beginners will become less stressful, leading to fewer lost grids and more successful imaging as they prepare their first samples. And we repair our Cryo-Tweezers for much less than the price of a new pair (click for details)!\u003c\/p\u003e\n\u003cp\u003eSpring-loaded Plunge Clamp: The Vitrobot tweezers interface with the FEI Vitrobot plunger with a dovetail geometry.  The tight mate of the dovetail makes it difficult to attach and detach the tweezers, and is sometimes difficult to control, leading to crashing the sample grid into the ethane cup walls.  Our Plunge-Clamp is spring loaded and when pinched open is easy to attach to, and remove from, the plunge arm.  When closed in its natural state, the clamp attaches securely to the dovetail at the end of the plunge arm.  The clamp self-centers to align the tweezers axis with the axis of the plunger rod to ensure that it plunges safely through to the liquid ethane.\u003c\/p\u003e\n\u003cp\u003eModified Reverse-Action Tweezers: The FEI Vitrobot tweezers are positive action, so an \"O-ring\" is utilized to keep the tweezers closed on the sample grid.  This requires you to carefully slide the O-ring up and down the tweezers, while holding the tips closed, whenever you want to grab or release the grid.  Our reverse action tweezers hold the grid securely in their natural state and require just a small pinch to release the grid into the grid box. Commercially available reverse-action tweezers are too wide for the Vitrobot blotting arms - our modified version fits between the blotting pads without interfering with the blot.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49095497842939,"sku":"17021002","price":685.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-CRYOT_1.jpg?v=1786644646"},{"product_id":"tweezer-repair","title":"Tweezer Repair","description":"\u003cp\u003eDespite treating tweezers with great care, inevitably, their continued use can lead to damage, particularly to the tips.  Damaged tips on tweezers used for plunge freezing make handling the grid difficult, leading to dropped grids, wasted time, wasted sample, etc.  There have always been two options: buy tweezers, then machine and assemble them yourself (and hope they don't interfere with blotting!), or pay full price for a brand new Tweezer assembly. \u003c\/p\u003e\u003cp\u003eNanoSoft has introduced a new option - send in your damaged Vitrobot Tweezers (including our CryoTweezers for the Vitrobot, at a reduced price) and receive them back like new.  We will refurbish the tweezer tips to as good as new.  Our repair service spares you the time and headache of trying to refurbish your own tweezers, and at a significant discount from the price of new Vitrobot Tweezers.  \u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"NanoSoft Cryo-Tweezers","offer_id":49095497875707,"sku":"20021001","price":150.0,"currency_code":"USD","in_stock":true},{"title":"Other Vitrobot Tweezers","offer_id":49095497908475,"sku":"20021003","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/a7322e_f9cf0120be3c4c409015d48a9387d83a_mv2.jpg?v=1785154444"},{"product_id":"vitrification-foam-dewar-with-metal-parts","title":"Vitrification Foam Dewar with Metal Parts","description":"\u003cp\u003eNanoSoft's foam Vitrification Dewar and Metal Parts are compatible with the Vitrobot, and can also provide a robust and easy option for custom, home-made cryoEM sample preparation systems. Furthermore, our parts are interchangeable with FEI parts, i.e. our foam dewar works with FEI metal parts and our metal parts work with the FEI foam dewar. Our foam dewar, developed in collaboration with Spearlab (patent # 7,971,744), provides a well-priced, easy to acquire, robust dewar for cryoEM sample preparation. The design provides an improved interface, such that the Igloo creates a better seal on our dewar containing boiled, cold nitrogen gas in the head space above the dewar allowing for safer grid transfer to the grid box.\u003c\/p\u003e\u003cp\u003eOur Grid Box Ring sits at the same height as the Vitrobot version (so grid boxes sit at same depth into dewar) but is slightly thicker and remains in contact with liquid nitrogen longer if the nitrogen level gets low.  Our ethane cup dimensions mimic those of the Vitrobot ethane cup, and the spider as well. We offer these parts that perform just as well with the Vitrobot, but at a more generous price than other options. \u003c\/p\u003e\u003cp\u003eThis listing bundles the foam dewar together with the metal parts set. For the foam dewar on its own, see the \u003ca href=\"\/products\/vitrification-foam-dewar\"\u003eVitrification Foam Dewar\u003c\/a\u003e.\u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49285270995195,"sku":"21021006","price":975.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/files\/nanosoft-21021006-1_4102b7f4-2323-4b35-b93e-81097ea62c99.jpg?v=1788965429"},{"product_id":"spt-labtech-chameleon","title":"SPT Labtech Chameleon","description":"\u003cp\u003eUsed Chameleon blot-free cryoEM sample preparation system. Very lightly used unit in great physical condition and worked well when last used. Requires reinstallation and updated maintenance from SPT Labtech engineers. \u003c\/p\u003e","brand":"NanoSoft","offers":[{"title":"Default Title","offer_id":49329617895675,"sku":null,"price":58000.0,"currency_code":"USD","in_stock":true}]},{"product_id":"gatan-cryoplunge-3","title":"Gatan Cryoplunge 3","description":"\u003cp\u003eMostly functional Gatan CP3 plunge freezer. Incredibly easy to use, with easy ability to manually blot. Ethane temperature control is not functioning\u003c\/p\u003e","brand":"Gatan","offers":[{"title":"Default Title","offer_id":49329656758523,"sku":null,"price":19000.0,"currency_code":"USD","in_stock":true}]}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0813\/8250\/6747\/collections\/Vitrification_White_noBR_horizPadding.svg?v=1785868590","url":"https:\/\/nanosoftcryo.com\/collections\/vitrification-tools.oembed","provider":"NanoSoft","version":"1.0","type":"link"}